Endothelin-1

A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)

Also Known As:

Endothelin 1; Big Endothelin; Big Endothelin-1; Endothelin Type 1; Endothelin, Big; Preproendothelin; Preproendothelin-1; Proendothelin (1-38); Proendothelin-1 Precursor; Big Endothelin 1; Endothelin-1, Big; Precursor, Proendothelin-1; Preproendothelin 1; Proendothelin 1 Precursor

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Endothelins: 4652
      - Endothelin-1: 6382
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Endothelins: 4652
      - Endothelin-1: 6382
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Endothelins: 4652
    - Endothelin-1: 6382

J D Sparkes Selected Research

J D Sparkes Research Topics

Disease

Drug/Important Bio-Agent (IBA)